For the most part people in Egypt are very kind and respectful. But understand that as a visitor from a foreign nation you will be the subject of curiosity pretty much everywhere you go. I’ve learned to accept this without taking offense. After all, my own curiosity is what spurs me to exploration.
This advice is not unique to Egypt, but an important recommendation for all your foreign travels; please make sure your US passport is valid for at least 6 months beyond your expected return date to the US.
US Citizens traveling to Egypt can obtain a tourist visa at the airport upon arrival for ~$25.
No vaccines are required for US citizens traveling to Egypt. However, Hepatitis A and Typhoid vaccines are recommended for all travelers. You should consult your physician as you may have additional risk factors. More information regarding the CDC’s immunization recommendations for Egypt can be found at: http://wwwnc.cdc.gov/travel/destinations/traveler/none/egypt
The currency in Egypt is the Egyptian Pound. You can get a few pounds before you leave home. Also, note that you’ll receive a better rate changing dollars for pounds at banks or currency exchange shops than you will get at reception desks in hotels or by paying with US dollars in restaurants or shops.
Ideally you’ll want to carry lots of small bills and coins. Your average taxi driver or street vendors will not have change for large bills. And you will also need small bills for tipping. (See more on tipping below) Use your big bills at larger stores, hotels or restaurants. Also, it’s very, very difficult to get small change so try and get as much as you can before arriving. And I also like to carry US dollars in small denominations as well.